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Locations
1085 Saint Matthews Rd.
Orangeburg, SC 29115
  1. Monday
    9am - 5pm
  2. Tuesday
    9am - 5pm
  3. Wednesday
    9am - 5pm
  4. Thursday
    9am - 5pm
  5. Friday
    9am - 5pm
  6. Location has an ATM.
  7. Location has a drive-thru.
First Bank branch sign.

Welcome to First Bank Orangeburg, SC!

We are pleased to be the community bank of choice for Orangeburg, SC. Here you’ll find straightforward advice from our local financial experts and sophisticated financial products to keep your accounts on the right track. We offer personal banking, business banking, digital and mobile banking, mortgage loans, business loans, and wealth management services.

At First Bank, we offer the same services as the big banks, but with personalized service from bankers who know your name and live in your neighborhood.

  • Deposits and Other Transactions
  • Commercial Loan Advisors
  • Business Solution and Treasury Specialists
  • Home Loan Professionals Available by Appointment
Headshots of various people with a power icon.

We believe in the
power of people.

Together with our customers, we’re
creating a world where individuals
and communities thrive.
Discover Our Initiatives

Featured Articles

Small Business Startup Loans – South Carolina

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Your Top 5 Tips for Effective Online Money Management

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How Much Should I Have in Savings at Age 35?

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No need to worry about making it to the bank before the doors close to deposit a check. If you have a bank with easy mobile deposit services such as First Bank in Salisbury, North Carolina, you can make the deposit from...

The Best Personal Banking Services for You

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HSA Rules and Regulations You Should Know

If you have a high-deductible health insurance plan, a Health Savings Account (HSA) can help you save for future medical expenses. Health Savings Accounts were established by the federal government as part of the Medicare...

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A bank’s objective is to relieve you of the stress associated with managing your money. But sometimes, people can feel like their bank is only adding more stress by making customers jump through hoops just to keep their...