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Locations
1085 Saint Matthews Rd.
Orangeburg, SC 29115
  1. Monday
    9am - 5pm
  2. Tuesday
    9am - 5pm
  3. Wednesday
    9am - 5pm
  4. Thursday
    9am - 5pm
  5. Friday
    9am - 5pm
  6. Location has an ATM.
  7. Location has a drive-thru.
First Bank branch sign.

Welcome to First Bank Orangeburg, SC!

We are pleased to be the community bank of choice for Orangeburg, SC. Here you’ll find straightforward advice from our local financial experts and sophisticated financial products to keep your accounts on the right track. We offer personal banking, business banking, digital and mobile banking, mortgage loans, business loans, and wealth management services.

At First Bank, we offer the same services as the big banks, but with personalized service from bankers who know your name and live in your neighborhood.

  • Deposits and Other Transactions
  • Commercial Loan Advisors
  • Business Solution and Treasury Specialists
  • Home Loan Professionals Available by Appointment
Headshots of various people with a power icon.

We believe in the
power of people.

Together with our customers, we’re
creating a world where individuals
and communities thrive.
Discover Our Initiatives

Featured Articles

Community Partners: Relay for Life and the Montgomery Square Branch

More than a decade ago, the staff at First Bank’s Montgomery Square branch in Troy, NC, began partnering with the local Montgomery County Relay for Life organization.

Money Mule Scams: How Criminals Convert Fraud into Profit

What is a Money Mule? Money mules are individuals who unknowingly or knowingly assist criminals in laundering money, often by transferring illegally sourced funds between accounts or across borders. The source of the money...

Best Small Business Bank – Albemarle, NC

If you’re looking for the best small business bank in Albemarle, NC—the search stops with First Bank. As a local bank, First Bank has a reputation for being an instrumental part of small businesses. Our proven history of...

Banks in North Carolina

Did you know there are more than 100 First Bank locations in North Carolina? It’s true. You can find us in over 60 cities, mountains to coast. Did you know we’re one of the oldest banks in North Carolina? Yup, our roots...

Credit Card Processing for Businesses

If you are a business owner, you probably know that accepting multiple forms of payment (cash, debit, credit, and checks) is important. But you may not know just how essential credit card processing is to the success of...

The Taxman Cometh

Do you have a stack of forms sitting on your counter that you’re dreading sorting through? If so, you might have FOTM, or Fear of the Tax Man. It can often hit around February or March, and is incredibly common. One way of...

How to Get a Home Equity Line of Credit

If you are thinking about taking out a loan to finance a major expense, such as home repairs or college tuition, a home equity line of credit (HELOC) or loan could be a good option. With a home equity line of credit, you...

The Changing Face of the Retail Experience

For while retailers face seemingly infinite choice, competition, and technology, retail is still at its strongest when it is focused on the basics: people, service, and relationships.

South Carolina Industries and Their Economic Impact [INFOGRAPHIC]

Check out this South Carolina infographic to learn more about areas for job growth and business opportunities.

Finding Success Amidst Uncertainty: Lessons from Anne Till

Navigate business ownership’s unknown risks with confidence. Here are 3 pieces of advice from Anne Till, owner of Anne Till Nutrition Group, to help you thrive as an entrepreneur.
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